Levitra 5mg Film-coated Tablets

Hepatic impairment A starting dose of 5 mg should be considered in patients with mild and moderate hepatic impairment Child-Pugh A-B. These effects are consistent with the vasodilatory effects of PDE5-inhibitors and are probably due to increased cGMP levels in vascular smooth muscle cells. This information dosage intended for use by health professionals. Penile Haemorrhage Haematospermia. Syncope Seizure Amnesia. Gastro-oesophageal reflux disease. Please note: The following patient groups were represented: Vardenafil dose adjustment might be necessary if moderate CYP3A4 inhibitors such as erythromycin and clarithromycin, are given concomitantly see sections levutra. There is no relevant indication for use of Levitra in children. Also the stimulation of the penis will be enough. Levitra 5 mg film-coated tablets Levitra 10 mg film-coated tablets Levitra 20 mg film-coated tablets. There are no studies of vardenafil in pregnant women. In men older than 75 years the concomitant use of vardenafil with itraconazole or ketoconazole is contraindicated see section 4. The median time to reach C max varied between 45 to 90 minutes and was similar or slightly delayed by 8 to 45 min compared to the film-coated tablets. Vardenafil AUC is not affected. Monday - Saturday - 8: Of these, patients have been treated for one year or longer. Single oral doses of 10 mg and 80 mg of vardenafil have been shown to prolong the QTc interval by a mean of 8 msec and 10 msec, respectively, levitra dosage. Allergic oedema and angioedema. Continue typing to refine. Penile haemorrhage, haematospermia and haematuria have been reported in clinical trials and spontaneous post-marketing data with the use of all PDE5 inhibitors, including vardenafil. Levitra ritonavir, a single dose of 2. In clinical dosage vardenafil was administered levifra over 17, men with erectile dysfunction ED aged 18 - levitra years, many of whom had multiple co-morbid lebitra. Mechanism of Levitra action on dosage organism The drug resolves problems with erectile function and enables levitra man to hold sexual intercourse.

Dosage those patients who are stable on alpha-blocker therapy, vardenafil should be initiated at the lowest recommended starting dose of 5 mg. See section 4. The interaction is a consequence of blocking hepatic metabolism of vardenafil by ritonavir, a highly potent CYP3A4 inhibitor, which also inhibits CYP2C9. After the taking of fourfold excess of the maximum dose 80 mg the volunteer noted leviyra pain in the lumbar spine. Levitra dosagw not indicated for individuals below 18 years of age. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or levitra. Concomitant treatment with vardenafil should only be initiated if the patient has been stabilised on his alpha-blocker therapy. Distributed in the United Kingdom by: Ear and labyrinth disorders. Date of first authorisation: The recommended dosage is 10mg; it should be taken 30 minutes prior to sex. Enter medicine levutra or company Start typing to retrieve search dosagge. Pharmacotherapeutic group: To bookmark a medicine you must sign up and log in. Film-coated tablet. The drug increases the blood flow in the cavernous bodies during sexual arousal and contributes to stable erection in men. Concomitant use with nitrates and nitric oxide donors in any form is contraindicated levitra Contraindications 4. In pooled data from the major efficacy trials, the proportion of patients experiencing successful penetration on vardenafil were as follows: Cimetidine mg twice eosagelevitra dosage, a non-specific cytochrome P inhibitor, had no effect on vardenafil AUC and C max when co-administered with vardenafil 20 mg to healthy volunteers.

The patient shall be responsible for the side effects of such mixtures. The maximum dose in patients with moderate hepatic impairment should not exceed 10 mg. Slowing the action of the enzyme, Levitra restores natural and normal process that occurs at sexual arousal. If the patient administrates other drugs, the dosage Levitra should not exceed 5 mg. If there is no effect, the dose may be increased up to 20 dosage. The dosage of Vardenafil is also 5 mg in the case of hepatic failure. Enter medicine name or company Start typing to retrieve search suggestions. Based on the results of interaction studies conducted with vardenafil in patients with benign prostatic hyperplasia BPH on stable tamsulosin, levitra dosage, levitra or alfuzosin therapy: Parts of M1 are in the form of the glucuronide in systemic circulation. Adjustment of drug dosage Pills are available in dosages of 5, 10, 20 mg. Influence of Levitra on organism It will be useful to know the mechanism of action of Levitra if Levitra or levitra PDE-5 inhibitors are prescribed. Dosage of 5 mg should be administrated at reduced liver function. All rights reserved. A time interval between dosing should be considered when Levitra dosage prescribed concomitantly with alpha-blocker therapy [see Clinical Pharmacology The safety of vardenafil has not been studied in the following sub-groups of patients and its use is therefore contraindicated until further information is available: It is not recommended to drive a car if you have one of the side effects listed in these instructions. During sexual stimulation, nitric oxide is released. Based on tolerability and efficacy, the dose may subsequently be increased. Date of revision of the text.

Tabulated list of adverse reactions Adverse reactions are listed according to the MedDRA frequency convention: Based on efficacy and tolerability the dose may be increased to 20 mg or decreased to 5 mg. Description of selected adverse reactions. Contraindications and advices for Verdenafil intake In some cases, it is contraindicated to use the tablets: Co-administration of ketoconazole mga potent CYP3A4 inhibitor, with vardenafil 5 mg resulted in a fold increase in vardenafil AUC and a 4-fold increase in vardenafil C max see section 4. There is a risk of adverse reactions or complications during the use of Levitra in case of any chronic cardiovascular diseases, so you need to consult a physician. Effect on bleeding In vitro studies with human platelets indicate that vardenafil has no antiaggregatory effect levitra its own, but at high super-therapeutic concentrations vardenafil potentiates the antiaggregatory effect of the nitric oxide donor sodium nitroprusside. Since alpha-blocker monotherapy can levitra marked lowering of blood pressure, especially postural hypotension and syncope, interaction studies were conducted with vardenafil. Distribution The mean steady state volume of distribution for vardenafil is l, indicating distribution into the tissues. Fatty food influences the time of activation of therapeutic action. Mechanism of Levitra action on man's organism dosage its features The drug allows you to treat a decrease or complete lack of erections in men. After oral administration the total duration of Levitra action reaches hours. Ritonavir significantly prolonged the half-life of vardenafil to Single and multiple oral doses of vardenafil up to 40 mg produced no clinically relevant changes in the ECGs of normal male volunteers. Ear and labyrinth disorders. Based on these results vardenafil 10 mg orodispersible tablets can be taken with or without food. It is strictly prohibited the administration of the drug to children under 16 years of age and women. One tablet contains Vardenafil weighing 5, 10, 20 mg, levitra dosage. After oral dosing of vardenafil AUC and Dosage max increase almost dose proportionally over the recommended dose range 5 — 20 mg. Visual disturbance Ocular hyperaemia Visual colour distortions Eye pain and eye discomfort Photophobia.

Levitra dosage

Search eMC: Concomitant treatment with vardenafil should only be initiated if the patient dosave been stabilised on his alpha-blocker therapy. If the patient administrates other drugs, the dosage Levitra should not exceed 5 mg. Parts of M1 are in the form of the glucuronide in systemic circulation. Leukemia, multiple myeloma, sickle cell anemia levitra be the risk factors in this case. The medicine should be kept in a dry cool place with levitra climate. To view the changes to a levihra you must sign up and log in. Although specific interaction studies have levitrs been conducted, the concomitant use of other dosaye CYP3A4 inhibitors such as itraconazole can be expected to produce vardenafil plasma levels comparable to those produced by ketoconazole. Lefitra properties 5. There is no relevant indication for use of Levitra in children. Main features of the medicine This medicine is intended to treat erectile dysfunction in men. Only the attending medical doctor may increase the dose and select it individually. The drug is used orally regardless of meals. In a clinical trial in patients with diabetes mellitus, vardenafil significantly improved the erectile function domain score, the ability to obtain and maintain an erection long enough for successful intercourse and penile rigidity compared to placebo at vardenafil doses of 10 mg and 20 mg. The recommended dose is 10 oevitra taken as needed approximately 25 to 60 minutes before sexual activity. Advantages of Levitra 1. There is no safety information available on the administration of vardenafil to patients with bleeding disorders or active peptic ulceration. The tablets should be kept in a cool dry place, levitra dosage, away from children. Skin and subcutaneous tissue disorders. No studies on the effects on the ability to drive and use machines have been performed. Paediatric population The European Medicines Agency has waived the obligation to submit the results of studies in all subsets of the paediatric population in the treatment of the erectile dysfunction. Dosage maximum expiry date of the drug is 3 years from the date of dosage. If the therapeutic dose has not brought the desired result, it may be increased to 20 mg. Maximum dosagee occurs within 1 hour.

The drug increases the blood flow in the cavernous bodies during sexual arousal and contributes to stable erection in men. For ritonavir, a single dose of 2. Active ingredient vardenafil hydrochloride. Toggle navigation. Ritonavir significantly prolonged the half-life of vardenafil to The maximum recommended dosing frequency is once per day. Other brands: This medicine is intended to treat erectile dysfunction in men. It is undesirable to use Levitra in the case of these diseases. Side effects should be eliminated at the delivery of health care. Older men should take the specified dosage. Date of first authorisation: The preparation absorbs in the stomach mucous and vosage preparation begins to act within 15 minutes after taking dosags tablet. The recommended dose is dosage mg taken as needed approximately 25 to 60 minutes before sexual activity. Vardenafil 10 mg orodispersible tablets must be taken without liquid, levitra dosage. Production date is indicated at the package. Analyses of observational data suggest an increased risk of acute NAION in men with erectile dysfunction following exposure to PDE5 inhibitors such as vardenafil, tadalafil and sildenafil see section 4. The drug resolves problems with erectile function and enables a man to hold sexual intercourse. Although a specific interaction study has not been conducted, the co-administration of clarithromycin can be expected to result in similar effects on vardenafil AUC and C max. Monday - Saturday - 8: You should ask your doctor if levitra have questions regarding this material.

Medically reviewed on November 12, The action may last 5 hours. Pharmacological properties 5. However, an increase to a maximum 20 mg dose should be carefully considered depending on the individual tolerability see sections 4. In vivo studies Co-administration of the HIV protease levitra indinavir mg three times a daya potent CYP3A4 inhibitor, with levitra 10 mg film-coated tablets resulted in a fold increase in vardenafil AUC and a 7-fold increase dosage vardenafil C max. Leivtra eMC: Single and multiple oral doses of vardenafil up to 40 mg produced no clinically relevant changes in the ECGs of normal male volunteers. In humans the dosage major circulating metabolite M1 results from desethylation of vardenafil and is subject to further metabolism with a plasma elimination half-life of approximately 4 hours. Distribution The mean steady state volume of distribution for vardenafil is l, indicating distribution into the tissues. One tablet contains from 5 to 20 mg of the active ingredient vardenafil. Legal Category POM: Pharmaceutical form 4. Continue typing to refine. This medicine is levitra to treat erectile dysfunction in men. Method dosage administration Levitea oral use. Vardenafil was not found to accumulate in the plasma in patients aged 45 years and below or 65 years or dosag following once-daily dosing of vardenafil 10 mg orodispersible eosage over ten days. Dosage of 5 mg should be administrated at leitra liver function. Dyspnoea Sinus congestion. The safety of vardenafil has not been studied in the following sub-groups of patients and its use is therefore contraindicated until further information is available:. Vardenafil AUC is not affected. Single oral doses of 10 mg and 80 mg of doaage have been shown to prolong the QTc interval by a mean of 8 msec and 10 msec, respectively.

Legal Category

In single dose volunteer studies, doses up to and including 80 mg vardenafil film-coated tablets per day were tolerated without exhibiting serious adverse reactions. The process of erection is based on blood flow to the cavernous bodies of the penis. Main rules of Levitra taking Dosage drug is used orally regardless of meals. Over 2, patients have been treated with vardenafil for six months or longer. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at: In vitro studies with human platelets indicate that vardenafil has no antiaggregatory effect on its own, but at high super-therapeutic concentrations vardenafil potentiates the antiaggregatory effect of the nitric oxide donor sodium nitroprusside. Moxifloxacin mg was included as an active internal control. Dosage 10 mg film-coated tablets: The package contains one blister with levitra. Stepwise increase in alpha-blocker dose may be associated with further lowering of blood pressure in patients taking a phosphodiesterase PDE5 inhibitor including vardenafil. Based on measurements of vardenafil in semen of healthy subjects 90 minutes after dosing, not more than 0. Influence of Levitra on organism It will be useful to know the levitra of action of Levitra if Levitra or other PDE-5 inhibitors are prescribed, levitra dosage. Levitra studies showed additive systemic blood pressure lowering effect when PDE5 inhibitors were dosage with riociguat. Very often men often confuse this problem with a number of other diseases or individual peculiarities. There are no fertility data available. Prescription only medicine. Hypersensitivity to the active substance or to any of the excipients listed in section 6.

levitra (vardenafil)

Therefore, concomitant treatment should be initiated only if the patient is stable on his alpha-blocker therapy. Erection is achieved by filling of the cavernous bodies of the penis by blood. By clicking Subscribe, I agree to the Drugs. The combination should be avoided see section 4. Based on tolerability and efficacy, the dose may subsequently be increased. Based on efficacy and tolerability the dose may be increased to 20 mg or decreased to 5 mg. A starting dose of 5 mg should be considered in patients with mild and moderate hepatic impairment Child-Pugh A-B. For ritonavir, a single dose of 2. Medicine composition, therapeutic doses of the active ingredient Levitra is available in tablet form. Renal Impairment: Parts of M1 are in the form of the glucuronide in systemic circulation. Levitra Dosage Generic name: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. The intake of the tablet with 40 mg of active ingredient did not affect negatively. The whole process was studied in detail by a group of scientists, and they held clinical test series in which experimental animals rabbits and a control group of rats and male volunteers participated.

Prior to initiating any treatment for erectile dysfunction, physicians should consider the cardiovascular status of their patients, since there is a degree of cardiac risk associated with sexual activity see section 4. The median time to reach C max varied between 45 to 90 minutes and was similar or slightly delayed by 8 to 45 min compared to the film-coated tablets. Hepatic Impairment: Concomitant use is contraindicated [see Contraindications 4. Single oral doses of 10 mg and 80 mg of vardenafil have been shown to prolong the QTc interval by a mean of 8 msec and 10 msec, respectively. When using the individual correction formulae, none of the values were out of the limit. Qualitative and quantitative composition 3. Contraindications and advices for Verdenafil intake In some cases, it is contraindicated to use the tablets: In a specific study, where vardenafil 20 mg was co-administered with slow release nifedipine 30 mg or 60 mg in hypertensive patients, there was an additional reduction on supine systolic blood pressure of 6 mmHg and supine diastolic blood pressure of 5 mmHg accompanied with an increase in heart rate of 4 bpm. Influence of Levitra on organism It will be useful to know the mechanism of action of Levitra if Levitra or other PDE-5 inhibitors are prescribed. Immune system disorders. Levitra Images. Skin and subcutaneous tissue disorders. Concomitant use of alpha-blockers The concomitant use of alpha-blockers and vardenafil may lead to symptomatic hypotension in some patients because both are vasodilators. Due to the nitrate component it has the potential to have serious interaction with vardenafil. Sexual stimulation is therefore required for vardenafil to produce its beneficial therapeutic effects. All dosages are prescribed by the physician: By clicking Subscribe, I agree to the Drugs. Visual disturbance Ocular hyperaemia Visual colour distortions Eye pain and eye discomfort Photophobia. Reproductive system and breast disorders. Detailed information on this medicinal product is available on the website of the European Medicines Agency http: Self-administration, change in dose or deviation from its recommendations is strictly prohibited. If the patient administrates levitra drugs, the dosage Levitra levltra not exceed 5 mg. A time interval between dosing should be considered when Levitra is prescribed concomitantly with alpha-blocker therapy levitga Clinical Pharmacology Show table of contents Hide table of contents 1. The peak activity of the drug occurs within an hour after taking. Based on measurements of vardenafil in semen of healthy subjects 90 minutes after dosing, not more than 0. This information is intended for use by health dosage.

For the full list of excipients, see section 6. Cimetidine mg twice daily , a non-specific cytochrome P inhibitor, had no effect on vardenafil AUC and C max when co-administered with vardenafil 20 mg to healthy volunteers. Moxifloxacin mg was included as an active internal control. Non-arteritic anterior ischaemic optic neuropathy Visual defects. In vivo studies No potentiation of the blood pressure lowering effect of sublingual nitroglycerin 0. To view the changes to a medicine you must sign up and log in. Absorption In vardenafil film-coated tablets, vardenafil is rapidly absorbed with maximum observed plasma concentrations reached in some men as early as 15 minutes after oral administration. Hepatobiliary disorders. With other alpha-blockers, a time separation of dosing should be considered when vardenafil is prescribed concomitantly see section 4. Levitra menu Instruction for use Main features of the medicine Medicine composition Mechanism of Levitra action Pharmacokinetics Main rules of Levitra taking Cases of overdose Contraindications Side effects You should pay attention to Storage conditions. This mechanism is well studied and the active ingredient has passed all the necessary tests. One tablet contains Vardenafil weighing 5, 10, 20 mg. By continuing to browse the site you are agreeing to our policy on the use of cookies. Concomitant use of vardenafil with the potent CYP3A4 inhibitors ketoconazole and itraconazole oral form is contraindicated in men older than 75 years. Skin and subcutaneous tissue disorders. This pathology does not allow men having sex and leads to the deterioration of family relationships. The adverse reactions reported with Levitra film-coated tablets or 10 mg orodispersible tablets in clinical trials were generally transient and mild to moderate in nature. Penile Haemorrhage Haematospermia. And single doses of 10 mg vardenafil co-administered concomitantly with mg gatifloxacin, an active substance with comparable QT effect, showed levitra additive QTc effect of 4 msec when compared to either active substance alone. Gastrointestinal disorders. If there is arterial hypertension and diseases of the cardiovascular system in a history there is a need of a cardiologist consultation. Syncope Seizure Amnesia. The intake of the tablet with 40 mg of dosage ingredient did not affect negatively. Home levitra vardenafil. The active substance of Levitra is vardenafil. Psychiatric disorders. Vardenafil, as other analogues, absorbed rapidly.